Wulandari, Hardini (2019) Efek Pemberian Bubuk Kakao (Theobroma Cacao L) Terhadap Kadar Glukosa Darah Sewaktu Pada Tikus Sprague Dawley Diabetes Melitus Tipe 2. Undergraduate thesis, Politeknik Negeri Jember.
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Abstract
Diabetes mellitus is a group of metabolic disease characterized by increasing blood glucose levels. Diabetes mellitus is one of the diseases that must be treatedimmediately because it could cause complications. A treatment with nontherapy of pharmacology by the provision of cocoa powder (Theobroma cacao l) as blood glucose control. The purposed of this research was to know the effect of the cocoa powder (Theobroma cacao l) on random blood glucose levels in Sprague Dawley rats diabetes mellitus type 2. This experimental study used design pretest and post test with control group. The sample collection randomization to 5 in the treatment group, namely the control group negative, positive control, P1, P2, and P3. The sample used the 15 male Sprague Dawley rats 2-3 months old, weight 200-300 grams, and healthy rats (active). In the treatment group, the rats were given feed HFD (high-fat diet) during 5 weeks and then induced use streptozotocin with doses 30mg / kg bb (single dose). In a state of hyperglycemia, the rats were given through intervention cocoa powder oral doses 0,4 grams, 0,8 grams, and 1,2 grams for 2 weeks. The data that analyzed using One way annova and Pairet T Test. The result of paired T Test showing no significant difference between blood glucose levels neither before and after treatment (p > 0,05). The cocoa powder does not affect significantly in lowering random blood glucose levels in Sprague Dawley rats diabetes mellitus type 2
| Item Type: | Thesis (Undergraduate) | ||||||
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| Subjects: | 340 - Rumpun Ilmu Kesehatan > 350 - Ilmu Kesehatan Umum > 354 - Ilmu Gizi | ||||||
| Divisions: | Jurusan Kesehatan > Prodi D4 Gizi Klinik > Tugas Akhir | ||||||
| Depositing User: | Sri Supriyatiningsih | ||||||
| Date Deposited: | 06 Jan 2026 07:32 | ||||||
| Last Modified: | 06 Jan 2026 07:32 | ||||||
| URI: | https://sipora.polije.ac.id/id/eprint/49779 |
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