Pengaruh Pemberian Buah Kiwi (Acnitida Deliciosa) Terhadap Kadar Asam Urat Darah Tikus Putih (Rattus Norvegicus) Hiperurisemia

Dirgantari, Lenny Lesti (2015) Pengaruh Pemberian Buah Kiwi (Acnitida Deliciosa) Terhadap Kadar Asam Urat Darah Tikus Putih (Rattus Norvegicus) Hiperurisemia. Undergraduate thesis, Politeknik Negeri Jember.

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Abstract

Uric acid is anormal partof the blood and urine. Uric acid is produced from the breakdown and disposal of remains of certain foods that contain purine nucleotide sorderived from purine nucleotide sproduced by the body. One of the fruits that contain vitamin C which is kiwi with vitamin C 96,8 mg in 100 g fruit. The purpose of this study is analyze the effect of kiwi (Actinidia Deliciosa) on levels of uric acid in rats (Rattus norvegicus) induced potassium oksonat males. This research is true experimental pre-test -post-testwith control group design. The sample purpose is male Wistar rat saged 2 months, high-fat diet induced, and was given a dose of kiwi fruit 4,6g, 5,6g, and 6,5g/200 g BW rats, for 15 days. Data were analyzed by paired t test and ANOVA, followed by LSD test. There are differences in total urid acid levels before and after treatment in the treatment group 1, 2 and 3(p <0.05) with kiwi fruit dose of 4,6gr/200gr BW rats/day, 5,6g/200 g BW rats/days with and 6,5gr/200gr BW rats/day decreased by 9.4%, 15% and 21%. Giving kiwi cannot lower blood uric acid levels equivalent drug probenesid.

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