Pengaruh Pemberian Seduhan Rosella Dengan Bawang Dayak Terhadap Kadar Kolesterol Total Pada Tikus Dislipidemia

Firdaus, Aisyah (2022) Pengaruh Pemberian Seduhan Rosella Dengan Bawang Dayak Terhadap Kadar Kolesterol Total Pada Tikus Dislipidemia. Undergraduate thesis, Politeknik Negeri Jember.

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Abstract

Dyslipidemia is a disorder caused by disorders of plasma lipid metabolism which is  characterized by disturbances in the lipid fraction in plasma. Steeping rosella with Dayak  onions contains flavonoid antioxidants, vitamin C, sapotanins and pectin which can  reduce total cholesterol levels. This study aims to determine the effect of steeping rosella  with Dayak onions on total cholesterol levels in dyslipidemic rats. This type of research is  True Experimental with Pretest-Posttest Control Group design. This study used 21 male  wistar rats aged 2-3 months with a body weight of 100-300 grams. The rats were divided  into three control groups, namely the negative control group (K-) which was given a  standard diet of AD2, the positive control group (K+) was fed a high-fat diet and the  treatment group (P) was fed a high-fat diet along with rosella steeping with 10 ml of  Dayak onions. /rat/day. Data were analyzed using SPSS v.25 software. The results  showed that there was a significant difference in total cholesterol levels in dyslipidemic  rats between groups before the intervention (p=0.38), there was a significant difference  in total cholesterol levels in dyslipidemic rats between groups after the intervention  (p=0.43), there was no difference. which means total cholesterol levels in the treatment  group (P) before and after the intervention (p = 0.14), the results of the test of the  difference in blood cholesterol levels of dyslipidemic rats between groups before and  after the intervention there was a significant difference (p = 0.001). The conclusion of  this study is that the administration of rosella infusion with Dayak onions has an effect on  lowering cholesterol levels in dyslipidemic rat.

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